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Article

Conformation of the N-terminal segment of a monocysteine mutant of troponin I from cardiac muscle.

Biochemistry - 3 Jun 1997

Dong W J, Chandra M, Xing J, Solaro R J, Cheung H C

Abstract excerpt

A monocysteine mutant of cardiac muscle troponin I, cTnI(S5C/C81I/C98S), was generated from a mouse cTnI cDNA clone and expressed in a bacterial system. Cys-5 was modified with the fluorescent sulfhydryl reagent IAANS to probe the conformation of the N-terminal extension of the mutant and the mutant complexed with cardiac muscle troponin C. Our emphasis was on the effect of phosphorylation of Ser-23 and Ser-24 by...

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Identifiers

PMID: 9184156
DOI: 10.1021/bi962226d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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