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Article

The functional significance of the last 5 residues of the C-terminus of cardiac troponin I.

Archives of biochemistry and biophysics - 1 Jul 2016

Gilda Jennifer E, Xu Qian, Martinez Margaret E, Nguyen Susan T, Chase P Bryant, Gomes Aldrin V

Abstract excerpt

The C-terminal region of cardiac troponin I (cTnI) is known to be important in cardiac function, as removal of the last 17 C-terminal residues of human cTnI has been associated with myocardial stunning. To investigate the C-terminal region of cTnI, three C-terminal deletion mutations in human cTnI were generated: Δ1 (deletion of residue 210), Δ3 (deletion of residues 208-210), and Δ5 (deletion of residues...

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Identifiers

PMID: 26919894
DOI: 10.1016/j.abb.2016.02.023
PMCID: PMC4899223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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