Structure of the troponin complex. Implications of photocross-linking of troponin I to troponin C thiol mutants.

Article

Structure of the troponin complex. Implications of photocross-linking of troponin I to troponin C thiol mutants.

The Journal of biological chemistry - 25 Feb 1994

Kobayashi T, Tao T, Gergely J, Collins J H

Abstract excerpt

Ca2+ regulation of vertebrate-striated muscle contraction is initiated by conformational changes in the Ca(2+)-binding protein troponin C (TnC) and subsequent changes in the interaction of TnC with the inhibitory protein TnI. We have constructed mutants of rabbit skeletal muscle TnC in which natu...

Topics

Amino Acid Sequence
Animals
Cross-Linking Reagents
Molecular Sequence Data
Mutation
Photochemistry
Protein Conformation
Rabbits
Sulfhydryl Compounds
Troponin
Troponin C
Troponin I

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.