Article
The Cmv1 host resistance locus is closely linked to the Ly49 multigene family within the natural killer cell gene complex on mouse chromosome 6.
Genomics - 1 May 1997
Forbes C A, Brown M G, Cho R, Shellam G R, Yokoyama W M, Scalzo A A
Abstract excerpt
Natural killer (NK) cells play important roles in controlling tumor cells and against a range of infectious organisms. Recent studies of mouse NK cell surface receptors, which may be involved in the specificity of NK cells, have shown that many of these molecules are encoded by the Ly49 and Ly55...
Topics
- Animals
- Base Sequence
- Chromosome Mapping
- Crosses, Genetic
- DNA Primers
- Female
- Genetic Linkage
- Killer Cells, Natural
- Male
- Mice
- Mice, Inbred A
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Microsatellite Repeats
- Multigene Family
- Muromegalovirus
- Phenotype
- Receptors, Immunologic