Article
Use of inbred mouse strains to map recognition receptors of MCMV infected cells in the NK cell gene locus.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Fodil-Cornu Nassima, Pyzik Michal, Vidal Silvia M
Abstract excerpt
Genetically distinct inbred strains of mice that differ in their susceptibility to mouse cytomegalovirus (MCMV) are invaluable for dissecting complex host-pathogen interactions. Their study has allowed the identification of host-resistance loci, including several activating NK cell receptors of major histocompatibility complex (MHC) class I. In this chapter, we provide a practical guide to the genetic mapping and...
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