Use of inbred mouse strains to map recognition receptors of MCMV infected cells in the NK cell gene locus.

doi:10.1007/978-1-60761-362-6_27

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Article

Use of inbred mouse strains to map recognition receptors of MCMV infected cells in the NK cell gene locus.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

Fodil-Cornu Nassima, Pyzik Michal, Vidal Silvia M

Abstract excerpt

Genetically distinct inbred strains of mice that differ in their susceptibility to mouse cytomegalovirus (MCMV) are invaluable for dissecting complex host-pathogen interactions. Their study has allowed the identification of host-resistance loci, including several activating NK cell receptors of major histocompatibility complex (MHC) class I. In this chapter, we provide a practical guide to the genetic mapping and...

Topics

Analysis of Variance
Animals
Cell Line
Chromosome Mapping
Cloning, Molecular
DNA, Complementary
Female
Gene Expression Regulation
Genetic Loci
Genetic Markers
Genome
Genotype
Immunity, Innate
Killer Cells, Natural
Male
Mice
Mice, Inbred Strains
Muromegalovirus

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Open in PubMed

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PMID: 20033656
DOI: 10.1007/978-1-60761-362-6_27

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