Article
A 2-Mb YAC contig and physical map of the natural killer gene complex on mouse chromosome 6.
Genomics - 15 May 1997
Brown M G, Fulmek S, Matsumoto K, Cho R, Lyons P A, Levy E R, Scalzo A A, Yokoyama W M
Abstract excerpt
We have constructed a physical map of a > 2-Mb region on mouse chromosome 6 that contains the natural killer gene complex (NKC). The map comprises a contig of 14 overlapping yeast artificial chromosomes onto which we positioned 25 NKC markers. NKC genetically linked genes encode > 17 proteins that directly control innate NK cell-mediated tumor lysis and disease resistance. Herein we show that Nkrp1 genes are...
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