Concerted nonsyntenic allelic losses in hyperploid hepatocellular carcinoma as determined by a high-resolution allelotype.

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Article

Concerted nonsyntenic allelic losses in hyperploid hepatocellular carcinoma as determined by a high-resolution allelotype.

Cancer research - 15 May 1997

Boige V, Laurent-Puig P, Fouchet P, Fléjou J F, Monges G, Bedossa P, Bioulac-Sage P, Capron F, Schmitz A, Olschwang S, Thomas G

Abstract excerpt

Although the occurrence of loss of genetic material in hepatocellular carcinoma (HCC) has been documented both by cytogenetic analysis and by monitoring of allelic losses, a global overview of the extent and frequency of deletion occurring throughout the genome is not yet available. To contribute...

Topics

Adult
Aged
Alleles
Aneuploidy
Carcinoma, Hepatocellular
Cell Separation
DNA, Neoplasm
Female
Gene Deletion
Heterozygote
Humans
Liver Neoplasms
Male
Middle Aged
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 9157995

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9157995-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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