Article
Allelotype study of primary hepatocellular carcinoma.
Cancer research - 1 Jan 1991
Fujimori M, Tokino T, Hino O, Kitagawa T, Imamura T, Okamoto E, Mitsunobu M, Ishikawa T, Nakagama H, Harada H
Abstract excerpt
Accumulation of mutations in oncogenes and tumor suppressor genes transforms a normal cell to a malignant cell by allowing it to escape from normal control of growth. In order to learn (a) how many tumor suppressor genes are involved in the tumor progression of hepatocellular carcinoma, (b) whether there is any association among allelic losses of chromosomes, or (c) whether integration of hepatitis B virus into...
Topics
- Alleles
- Carcinoma, Hepatocellular
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 16
- Chromosomes, Human, Pair 17
- DNA, Neoplasm
- DNA, Viral
- Hepatitis B virus
- Humans
- Liver Neoplasms