Article
Clinicopathological significance of loss of heterozygosity on chromosome 13q in hepatocellular carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2002
Wong Chun Ming, Lee Joyce Man Fong, Lau Tracy Ching Man, Fan Sheung Tat, Ng Irene O L
Abstract excerpt
PURPOSE: Allelic loss is the most frequently genetic alteration found in hepatocellular carcinoma (HCC). Previous genome-wide studies have indicated that chromosome 13q is one of the most frequently affected chromosomes. However, reports on detailed deletion mapping as well as detailed clinicopathological correlation are scanty. EXPERIMENTAL DESIGN: We performed high-density allelotyping on chromosome 13q in HCC...
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