Article
High-density allelotyping of chromosome 8p in hepatocellular carcinoma and clinicopathologic correlation.
Cancer - 15 Jun 2002
Chan Kok-Lung, Lee Joyce Man-Fong, Guan Xin-Yuan, Fan Sheung-Tat, Ng Irene Oi-Lin
Abstract excerpt
BACKGROUND: Allelic deletions are frequent genetic alterations in patients with hepatocellular carcinoma (HCC). METHODS: To evaluate the allelic losses on chromosome 8p in HCC patients and define their clinicopathologic significance, we performed high-density allelotyping on 8p in 60 patients with HCC and analyzed the clinicopathologic correlation. RESULTS: Using 24 microsatellite markers, allelic losses on 8p...
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