Article
Evaluation of genetic tests: APOE genotyping for the diagnosis of Alzheimer disease.
Genetic testing - 1 Jan 1999
McConnell L M, Sanders G D, Owens D K
Abstract excerpt
Many studies have now confirmed the association between inheritance of the epsilon 4 allele of the apolipoprotein E (APOE) gene and Alzheimer disease (AD). However, although the medical community holds the near-unanimous opinion that APOE genotyping should not be used for prediction in asymptomatic individuals, controversy remains about whether it should be used for diagnosis in patients who show signs of...
Topics
- Alzheimer Disease
- Apolipoproteins E
- Evaluation Studies as Topic
- Genetic Testing
- Genotype
- Humans