Article
Apolipoprotein E genotype and noncognitive symptoms in Alzheimer's disease.
Biological psychiatry - 15 Feb 1999
Levy M L, Cummings J L, Fairbanks L A, Sultzer D L, Small G W
Abstract excerpt
BACKGROUND: The apolipoprotein E (ApoE) epsilon 4 allele confers significant risk for Alzheimer's disease and is associated with a greater amyloid burden in the brain. Future treatments may target molecular mechanisms associated with this allele, and it is important to define any phenotypic characteristics that correspond to this genotype. We sought to clarify the relationship between ApoE status and noncognitive...
Topics
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Apolipoprotein E4
- Apolipoproteins E
- Behavioral Symptoms
- Chi-Square Distribution
- Cross-Sectional Studies
- Depression
- Female
- Gene Dosage