Article
Frequency and clinico-pathological associations of ras mutations in colorectal cancer in the Victorian population.
The Australian and New Zealand journal of surgery - 1 May 1997
Thomas R J, Liu Y S, St Clair F, Norris P M, Valentine R, Phillips W A
Abstract excerpt
BACKGROUND: Mutations in the oncogene ras occur in 20-50% of colorectal cancers. The presence of these mutations allows screening tests to be developed based on the identification of mutant DNA in cells derived from cancers. A study of the prevalence and clinicopathological associations of ras mu...
Topics
- Aged
- Chi-Square Distribution
- Colorectal Neoplasms
- DNA, Neoplasm
- Female
- Gene Frequency
- Genes, ras
- Humans
- Male
- Middle Aged
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Prevalence
- Victoria