Article
Clinico-pathological study of K-ras mutations in colorectal tumors in Saudi Arabia.
Tumori - 1 Jan 2000
Zahrani Ali, Kandil Magdy, Badar Talha, Abdelsalam Mahmoud, Al-Faiar Abdulla, Ismail Abdelsalam
Abstract excerpt
AIMS AND BACKGROUND: K-ras gene mutations contribute to the pathogenesis of colorectal cancer. We characterized K-ras mutations in colorectal tumors in patients in the Kingdom of Saudi Arabia, in terms of geographic area, age, gender, histology, stage, and anatomical localization. METHODS: Medical records and paraffin-embedded tumor samples from 150 consecutive patients with histologically proven colorectal...
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