Kirsten ras mutations in patients with colorectal cancer: the multicenter "RASCAL" study.

doi:10.1093/jnci/90.9.675

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Article

Kirsten ras mutations in patients with colorectal cancer: the multicenter "RASCAL" study.

Journal of the National Cancer Institute - 6 May 1998

Andreyev H J, Norman A R, Cunningham D, Oates J R, Clarke P A

Abstract excerpt

BACKGROUND: Kirsten ras (Ki-ras) gene mutations occur early in the progression of colorectal adenoma to carcinoma. The aim of this collaborative study was to clarify the association between Ki-ras mutations, patient outcome, and tumor characteristics by use of data from colorectal cancer patients...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Colorectal Neoplasms
Disease-Free Survival
Female
Genes, ras
Humans
Male
Middle Aged
Multivariate Analysis
Mutation
Neoplasm Staging
Odds Ratio
Predictive Value of Tests
Prognosis
Survival Analysis

Source

Open in PubMed

Identifiers

PMID: 9586664
DOI: 10.1093/jnci/90.9.675

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9586664-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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