Article
p53 and K-ras gene mutations in carcinoma of the rectum among Finnish women.
Molecular pathology : MP - 1 Feb 2000
Servomaa K, Kiuru A, Kosma V M, Hirvikoski P, Rytömaa T
Abstract excerpt
AIMS/BACKGROUND: The aim of this study was to identify p53 and K-ras gene mutations in carcinoma of the rectum among Finnish women. Mutation patterns might give clues to aetiological factors when comparisons are made with other human tumours. METHODS: Of 134 women with carcinoma of the rectum, paraffin wax embedded specimens of the tumour tissue were obtained from 118 patients. Genomic DNA was extracted, and...
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