Article
A comparison of somatic mutational spectra in healthy study populations from Russia, Sweden and USA.
Carcinogenesis - 1 Jun 2005
Noori Peri, Hou Saimei, Jones Irene M, Thomas Cynthia B, Lambert Bo
Abstract excerpt
A comparison of mutation spectra at the hypoxanthine-guanine phosphoribosyl transferase (HPRT) gene of peripheral blood T-lymphocytes may provide an insight into the aetiology of somatic mutation contributing to carcinogenesis and other diseases. To increase the knowledge of mutation spectra in healthy people, we have analysed HPRT mutant T-cells of 50 healthy Russians originally recruited as controls in a study...
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