Article
Russian mutational spectrum differs from that of their Western counterparts.
Human mutation - 1 Jan 2000
Curry J, Khaidakov M, Glickman B W
Abstract excerpt
It has been previously noted that the hypoxanthine-guanine phosphoribosyltransferase (HPRT) mutant frequency of Russian subjects is significantly higher than age-matched Western counterparts. To further explore this difference, approximately 100 mutants collected from Russian twins reported in a previous study have been sequenced and compared to an aged-matched Western mutant dataset. The mutational spectrum of...
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