Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 gene mutation analysis in porokeratosis and porokeratosis-associated squamous cell carcinoma.

Journal of dermatological science - 1 Mar 1997

Ninomiya Y, Urano Y, Yoshimoto K, Iwahana H, Sasaki S, Arase S, Itakura M

Abstract excerpt

In this and previous studies, we have shown p53 overexpression immunohistochemically in 14 of 17 porokeratotic specimens obtained from 14 lesions of nine cases, and in all six specimens of squamous cell carcinoma (SCC) arising on porokeratotic lesions of two cases. We screened mutations in exons 5 to 10 of the p53 gene in all these specimens by polymerase chain reaction-single strand conformation polymorphism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to DNA, Neoplasm
Share to Exons

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, p53

Share to Immunohistochemistry

Share to Mutation

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Source

Identifiers

PMID: 9138474
DOI: 10.1016/s0923-1811(96)00569-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 gene mutation analysis in porokeratosis and porokeratosis-associated squamous cell carcinoma.PMID 9138474Read ↗

p53 gene mutations in human skin cancers and precancerous lesions: comparison with immunohistochemical analysis.Semantic proximity Read ↗

p53 gene mutations in skin cancers with underlying disorders.Semantic proximity Read ↗

p53 gene mutations in human epithelial skin cancers.Semantic proximity Read ↗

Analysis of the p53 gene in human precancerous actinic keratosis lesions and squamous cell cancers.Semantic proximity Read ↗

p53 alterations in porokeratosis.Semantic proximity Read ↗

Mutations in the p53 tumor suppressor gene in human cutaneous squamous cell carcinomas.Semantic proximity Read ↗

p53 mutations are common and early events that precede tumor invasion in squamous cell neoplasia of the skin.Semantic proximity Read ↗

p53 alterations in chemically induced hamster cheek-pouch lesions.Semantic proximity Read ↗

Ultraviolet-specific mutations in p53 gene in skin tumors in xeroderma pigmentosum patients.Semantic proximity Read ↗

p53 gene mutations in Barrett's epithelium and esophageal cancer.Semantic proximity Read ↗

Analysis of p53 Mutations and the Expression of p53 and p21<sup>WAF1/CIP1</sup>Protein in 15 Cases of Sebaceous Carcinoma of the EyelidSemantic proximity Read ↗

Mutation and abnormal expression of the p53 gene in the viral skin carcinogenesis of epidermodysplasia verruciformis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.