Article
Mutation and abnormal expression of the p53 gene in the viral skin carcinogenesis of epidermodysplasia verruciformis.
The Journal of investigative dermatology - 1 Oct 2001
Padlewska K, Ramoz N, Cassonnet P, Riou G, Barrois M, Majewski S, Croissant O, Jablonska S, Orth G
Abstract excerpt
Patients suffering from epidermodysplasia verruciformis are prone to nonmelanoma skin cancers, due to an inherited abnormal susceptibility to the oncogenic human papillomavirus type 5. Genotoxic sunlight ultraviolet B radiations are likely to be a cofactor. Lesions of two human-papillomavirus-type-5-infected epidermodysplasia verruciformis patients collected during an 8 y period were retrospectively studied for...
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