p53 alterations in porokeratosis.

doi:10.1034/j.1600-0560.2003.00097.x

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Article

p53 alterations in porokeratosis.

Journal of cutaneous pathology - 1 Aug 2003

Arranz-Salas Isabel, Sanz-Trelles Andres, Ojeda Dolores Bautista

Abstract excerpt

BACKGROUND: Porokeratosis (PK) is a group of cutaneous entities characterized by disordered epidermal keratinization and by a predisposition to develop malignant transformation. The molecular mechanism of this carcinogenesis remains unclear, but p53 has been proposed as a mediator of this process. p53 overexpression, detected by immunohistochemistry, has frequently been reported in PK, and p53 mutations are...

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Share to Carcinoma, Squamous Cell
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PMID: 12859744
DOI: 10.1034/j.1600-0560.2003.00097.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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