Article
p53 alterations in chemically induced hamster cheek-pouch lesions.
Molecular carcinogenesis - 1 Aug 1996
Gimenez-Conti I B, LaBate M, Liu F, Osterndorff E
Abstract excerpt
To confirm that the hamster cheek-pouch carcinogenesis model reflects development of human squamous cell carcinoma (SCC), we determined if and when p53 mutations occur in the development of SCC in this model by using immunohistochemical staining and polymerase chain reaction (PCR)-single-strand conformation polymorphism (SSCP) analysis plus direct DNA sequencing. Twenty-four hamster cheek-pouches were treated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
