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Article

Analysis of the p53 gene in human precancerous actinic keratosis lesions and squamous cell cancers.

Cancer letters - 30 Sept 1994

Nelson M A, Einspahr J G, Alberts D S, Balfour C A, Wymer J A, Welch K L, Salasche S J, Bangert J L, Grogan T M, Bozzo P O

Abstract excerpt

A biomarker of skin cancer would be beneficial in evaluating the efficacy of potential cancer chemoprevention agents. To this end, we investigated the tumor suppressor gene p53 in precancerous actinic keratosis lesions (AK) and malignant squamous cell carcinomas (SCCs) using polymerase chain reaction and single-strand conformation polymorphism analysis (PCR-SSCP) techniques. In addition, p53 protein expression...

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PMID: 7923098
DOI: 10.1016/0304-3835(94)90234-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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