p56(chk1) protein kinase is required for the DNA replication checkpoint at 37 degrees C in fission yeast.

doi:10.1093/emboj/16.6.1332

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Article

p56(chk1) protein kinase is required for the DNA replication checkpoint at 37 degrees C in fission yeast.

The EMBO journal - 17 Mar 1997

Francesconi S, Grenon M, Bouvier D, Baldacci G

Abstract excerpt

Fission yeast p56(chk1) kinase is known to be involved in the DNA damage checkpoint but not to be required for cell cycle arrest following exposure to the DNA replication inhibitor hydroxyurea (HU). For this reason, p56(chk1) is considered not to be necessary for the DNA replication checkpoint wh...

Topics

Checkpoint Kinase 1
DNA Damage
DNA Replication
Hydroxyurea
Mutation
Phenotype
Phosphorylation
Protein Kinases
Schizosaccharomyces
Schizosaccharomyces pombe Proteins
Temperature
Tyrosine

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