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Article

Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity.

Molecular and cellular biology - 1 Nov 2000

Snaith H A, Brown G W, Forsburg S L

Abstract excerpt

The fission yeast Hsk1p kinase is an essential activator of DNA replication. Here we report the isolation and characterization of a novel mutant allele of the gene. Consistent with its role in the initiation of DNA synthesis, hsk1(ts) genetically interacts with several S-phase mutants. At the restrictive temperature, hsk1(ts) cells suffer abnormal S phase and loss of nuclear integrity and are sensitive to both...

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Identifiers

PMID: 11027263
DOI: 10.1128/MCB.20.21.7922-7932.2000
PMCID: PMC86403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity.PMID 11027263Read ↗

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