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Article

Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans.

Journal of pharmacokinetics and biopharmaceutics - 1 Oct 1996

Wilkinson G R

Abstract excerpt

CYP3A is one of the most important cytochrome P450 isoforms responsible for drug metabolism by humans because it is the major such enzyme in critical tissues such as the gastrointestinal tract and liver, and it is involved in the oxidative biotransformation of numerous clinically useful therapeutic agents. Many factors regulate CYP3A expression but these are being increasingly defined so that the disposition...

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PMID: 9131486
DOI: 10.1007/BF02353475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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