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Article

In vitro identification of cytochrome P450 enzymes responsible for drug metabolism.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Yan Zhengyin, Caldwell Gary W

Abstract excerpt

Metabolism catalyzed by the cytochrome P450 enzymes (CYPs) represents the most important pathway for drug metabolism and elimination in humans. Identification of the CYPs responsible for metabolism of existing and novel drugs is critical for the prediction of adverse reactions caused by drug-drug interactions or individual genetic polymorphism. An integrated approach is described for CYP-mediated metabolic...

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PMID: 23824861
DOI: 10.1007/978-1-62703-435-7_16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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