Article
Identification and characterization of neogenin, a DCC-related gene.
Oncogene - 13 Mar 1997
Meyerhardt J A, Look A T, Bigner S H, Fearon E R
Abstract excerpt
DCC (deleted in colorectal cancer), a candidate tumor suppressor gene located in chromosome band 18q21.2, encodes a transmembrane protein of 1447 amino acids. Neogenin, a protein with nearly 50% amino acid identity to DCC, was recently identified because of its dynamic expression in the developing nervous system and gastrointestinal tract of the chicken. To explore a role for the human neogenin (NGN) gene in...
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