Article
Identification and characterization of neogenin, a DCC-related gene.
Oncogene - 13 Mar 1997
Meyerhardt J A, Look A T, Bigner S H, Fearon E R
Abstract excerpt
DCC (deleted in colorectal cancer), a candidate tumor suppressor gene located in chromosome band 18q21.2, encodes a transmembrane protein of 1447 amino acids. Neogenin, a protein with nearly 50% amino acid identity to DCC, was recently identified because of its dynamic expression in the developin...
Topics
- Adult
- Alleles
- Amino Acid Sequence
- Animals
- Blotting, Northern
- Blotting, Western
- Chickens
- DNA, Complementary
- Gene Deletion
- Genes, DCC
- Humans
- Membrane Proteins
- Molecular Sequence Data