Article
Netrin-1: interaction with deleted in colorectal cancer (DCC) and alterations in brain tumors and neuroblastomas.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Jan 1999
Meyerhardt J A, Caca K, Eckstrand B C, Hu G, Lengauer C, Banavali S, Look A T, Fearon E R
Abstract excerpt
Netrins, a family of laminin-related secreted proteins, have critical roles in axon guidance and cell migration during development. The deleted in colorectal cancer (DCC) protein has been implicated as a netrin-1 receptor component. The expression and function of netrins in adult tissues remain u...
Topics
- Amino Acid Sequence
- Animals
- Brain Neoplasms
- COS Cells
- Caenorhabditis elegans
- Cell Line, Transformed
- Chromosome Mapping
- Colorectal Neoplasms
- Gene Expression
- Humans
- Mice
