Article
The complementary deoxyribonucleic acid sequence, tissue distribution, and cellular localization of the rat granulin precursor.
1 Dec 1993
Abstract excerpt
Granulins (grns; also called epithelins) are cysteine-rich polypeptides with pleiotropic effects on epithelial cell growth in vitro. The grn/epi gene is widely expressed in epithelial cell lines, many of which respond to the gene product, raising the possibility of autocrine or paracrine regulation. In vitro the grn gene is expressed in cell types of diverse lineages, including epithelial cells, lymphoid and...