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Article

Defining the ligand specificity of the deleted in colorectal cancer (DCC) receptor.

PloS one - 1 Jan 2014

Haddick Patrick C G, Tom Irene, Luis Elizabeth, Quiñones Gabriel, Wranik Bernd J, Ramani Sree R, Stephan Jean-Philippe, Tessier-Lavigne Marc, Gonzalez Lino C

Abstract excerpt

The growth and guidance of many axons in the developing nervous system require Netrin-mediated activation of Deleted in Colorectal Cancer (DCC) and other still unknown signaling cues. Commissural axon guidance defects are more severe in DCC mutant mice than Netrin-1 mutant mice, suggesting additional DCC activating signals besides Netrin-1 are involved in proper axon growth. Here we report that interaction...

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Source

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Identifiers

PMID: 24400119
DOI: 10.1371/journal.pone.0084823
PMCID: PMC3882260

Genes

DCC
CBLN4
NEO1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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