Article
Expression of p53 in adrenocortical tumours: clinicopathological correlations.
The Journal of pathology - 1 Feb 1997
McNicol A M, Nolan C E, Struthers A J, Farquharson M A, Hermans J, Haak H R
Abstract excerpt
There are limited data to suggest that abnormalities of p53 expression may be a late event in the development of adrenocortical tumours. This has been investigated further by examining a series of adrenocortical adenomas and carcinomas by immunohistochemistry for p53 expression and a subset for evidence of mutation in exons 5-8 of the p53 gene using polymerase chain reaction/single strand conformational...
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