Article
p53 abnormalities in human parathyroid carcinoma.
The Journal of clinical endocrinology and metabolism - 1 Jun 1994
Cryns V L, Rubio M P, Thor A D, Louis D N, Arnold A
Abstract excerpt
Two cell cycle regulators have been implicated in the pathogenesis of parathyroid neoplasms: rearrangement/overexpression of the PRAD1/cyclin D1 gene in parathyroid adenomas and inactivation of the retinoblastoma tumor suppressor gene in parathyroid carcinomas. We examined parathyroid tumors for evidence of molecular genetic abnormalities in another cell cycle regulator, the p53 tumor suppressor gene. Allelic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
