Expression and mutations of p53 in salivary gland tumours

Abstract excerpt

A series of 219 salivary gland tumours (103 carcinomas and 116 benign tumours) were analysed for p53 protein expression using immunohistochemistry, and for mutations in p53 gene using non-radioactive single strand conformation polymorphism (SSCP). p53 expression was present in 36% (42/116) of the benign tumours and in 54% (56/103) of the carcinomas. The highest prevalence of p53 expression was found in adenoid...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Head and Neck Surgical Oncology
• Share to Oral and Maxillofacial Pathology
• Share to Salivary Gland Tumors Diagnosis and Treatment