Article
Assessment of the DQB1-DQA1 complete genotype allows best prediction for IDDM.
Diabetes care - 1 Sept 1994
Tosi G, Facchin A, Pinelli L, Accolla R S
Abstract excerpt
OBJECTIVE: To analyze the HLA-DQ (human leukocyte antigen) genetic association with insulin-dependent diabetes mellitus (IDDM) patients of the Northeast Italian population. RESEARCH DESIGN AND METHODS: Fifty-one IDDM patients and 52 healthy control subjects were molecularly typed for DQB1 and DQA...
Topics
- Alleles
- Base Sequence
- DNA
- Diabetes Mellitus, Type 1
- Genetic Predisposition to Disease
- Genotype
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- Homozygote
- Humans
- Italy
- Molecular Sequence Data
- Polymerase Chain Reaction
- Predictive Value of Tests
