Analysis of HLA genotypes and susceptibility to insulin-dependent diabetes mellitus: HLA-DQ alpha complements HLA-DQ beta.

doi:10.1111/j.1365-3083.1992.tb03105.x

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Article

Analysis of HLA genotypes and susceptibility to insulin-dependent diabetes mellitus: HLA-DQ alpha complements HLA-DQ beta.

Scandinavian journal of immunology - 1 Aug 1992

Baisch J M, O'Brien M E, Hoover M L, Capra J D

Abstract excerpt

It is well known that certain genes in the HLA-D region confer increased susceptibility to insulin-dependent diabetes mellitus (IDDM). Previous studies have documented an increased risk associated with the HLA-DR beta chain alleles, DR3 and DR4, and the DQ beta chain allele DQB1*0302 (formerly DQ...

Topics

Alleles
Base Sequence
Diabetes Mellitus, Type 1
Gene Frequency
Genotype
HLA-DQ Antigens
HLA-DR Antigens
Humans
Molecular Sequence Data

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