Role of a genetic region on chromosome 4 in the regulation of natural killer cell activity in mice.

doi:10.1111/j.1744-313x.1993.tb00157.x

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Article

Role of a genetic region on chromosome 4 in the regulation of natural killer cell activity in mice.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Oct 1993

Dubey D P, Mirza N M, Zaharian B I, Yunis E J

Abstract excerpt

Natural killer cell (NK) activity is regulated by both the H-2 and non-H-2 genes. Using bilineal congenic HW26C and HW13 mice which differ from the background strain C57BL/6By (B6) in a region of chromosome 4, we investigated the role played by a gene/genes in a segment of chromosome 4 of BALB/cBy on NK cell activity. Percoll separated low density spleen cells from young HW26C and HW13 mice showed a 3.5 fold...

Topics

Animals
Cell Membrane
Chromosome Mapping
Cytotoxicity, Immunologic
Female
Immunogenetics
In Vitro Techniques
Killer Cells, Natural
Male
Mice
Mice, Inbred BALB C
Phenotype

Source

Open in PubMed

Identifiers

PMID: 9098406
DOI: 10.1111/j.1744-313x.1993.tb00157.x

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