Article
Genetic control of natural killing and in vivo tumor elimination by the Chok locus.
The Journal of experimental medicine - 21 Dec 1998
Idris A H, Iizuka K, Smith H R, Scalzo A A, Yokoyama W M
Abstract excerpt
The molecular mechanisms underlying target recognition during natural killing are not well understood. One approach to dissect the complexities of natural killer (NK) cell recognition is through exploitation of genetic differences among inbred mouse strains. In this study, we determined that inte...
Topics
- Alleles
- Animals
- Antigens
- Antigens, CD
- Antigens, Ly
- Antigens, Surface
- CHO Cells
- Cell Line
- Cricetinae
- Cytotoxicity, Immunologic
- Genetic Linkage
- Haplotypes
- Interleukin-2
- Killer Cells, Natural
- Lectins, C-Type
- Lymphocyte Activation
- Major Histocompatibility Complex
- Membrane Glycoproteins