Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic control of natural killing and in vivo tumor elimination by the Chok locus.

The Journal of experimental medicine - 21 Dec 1998

Idris A H, Iizuka K, Smith H R, Scalzo A A, Yokoyama W M

Abstract excerpt

The molecular mechanisms underlying target recognition during natural killing are not well understood. One approach to dissect the complexities of natural killer (NK) cell recognition is through exploitation of genetic differences among inbred mouse strains. In this study, we determined that interleukin 2-activated BALB/c-derived NK cells could not lyse Chinese hamster ovary (CHO) cells as efficiently as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Antigens, CD
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cricetinae

Share to Genetic Linkage

Share to Haplotypes

Share to Lymphocyte Activation

Share to Membrane Glycoproteins

Source

Open in PubMed Open full text

Identifiers

PMID: 9858511
DOI: 10.1084/jem.188.12.2243
PMCID: PMC2212436

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic control of natural killing and in vivo tumor elimination by the Chok locus.PMID 9858511Read ↗

Natural killer gene complex (Nkc) allelic variability in inbred mice: evidence for Nkc haplotypes.Semantic proximity Read ↗

Host genetic control of natural killer cell diversity revealed in the Collaborative Cross.Semantic proximity Read ↗

Regulation of the NK cell alloreactivity to bone marrow cells by the combination of the host NK gene complex and MHC haplotypes.Semantic proximity Read ↗

Molecular and genetic basis for strain-dependent NK1.1 alloreactivity of mouse NK cells.Semantic proximity Read ↗

Development of intra-natural killer complex (NKC) recombinant and congenic mouse strains for mapping and functional analysis of NK cell regulatory loci.Semantic proximity Read ↗

Widespread natural variation in murine natural killer T-cell number and function.Semantic proximity Read ↗

Interferon-gamma receptor polymorphisms determine strain differences in accessibility of activated lymphocyte NK-triggering antigens to recognition by self-reactive NK cells.Semantic proximity Read ↗

Mapping of the BALB/c Ly49 cluster defines a minimal natural killer cell receptor gene repertoire.Semantic proximity Read ↗

Control of rat natural killer cell-mediated allorecognition by a major histocompatibility complex region encoding nonclassical class I antigens.Semantic proximity Read ↗

NK gene complex haplotype variability and host resistance alleles to murine cytomegalovirus in wild mouse populations.Semantic proximity Read ↗

Natural killer-like T cells develop in SJL mice despite genetically distinct defects in NK1.1 expression and in inducible interleukin-4 production.Semantic proximity Read ↗

Genes in two major histocompatibility complex class I regions control selection, phenotype, and function of a rat Ly-49 natural killer cell subset.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.