Article
The antifertility effect of passive immunization of mice against progesterone is influenced by genetic factors other than H-2 haplotype.
The Journal of endocrinology - 1 May 1990
Nowak R A, Wang M W, Heap R B
Abstract excerpt
The anti-fertility effect of passive immunization against progesterone is influenced by genotype in mice. In order to quantify this finding we determined the effective dose that blocks pregnancy in 50% of treated mice (ED50) for two different anti-progesterone monoclonal antibodies (DB3 and 11/32...
Topics
- Animals
- Antibodies, Monoclonal
- Dose-Response Relationship, Drug
- Female
- Fertility
- Genotype
- Haplotypes
- Immunization, Passive
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Pregnancy
- Pregnancy, Animal
- Progesterone