Article
The antifertility effect of passive immunization of mice against progesterone is influenced by genetic factors other than H-2 haplotype.
The Journal of endocrinology - 1 May 1990
Nowak R A, Wang M W, Heap R B
Abstract excerpt
The anti-fertility effect of passive immunization against progesterone is influenced by genotype in mice. In order to quantify this finding we determined the effective dose that blocks pregnancy in 50% of treated mice (ED50) for two different anti-progesterone monoclonal antibodies (DB3 and 11/32) in four different strains of mice (BALB/cJ, CBA/Ca, Tuck's no. 1 and F1C). Efficacy was greatest in the two inbred...
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