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Article

Molecular and genetic basis for strain-dependent NK1.1 alloreactivity of mouse NK cells.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2006

Carlyle James R, Mesci Aruz, Ljutic Belma, Belanger Simon, Tai Lee-Hwa, Rousselle Etienne, Troke Angela D, Proteau Marie-France, Makrigiannis Andrew P

Abstract excerpt

NK1.1 alloantigen expression can be used to define NK cells in certain mouse strains, such as B6 (NKR-P1C) and SJL (NKR-P1B). However, BALB/c NK cells do not react with the anti-NK1.1 mAb, PK136. To investigate the NK1.1(-) phenotype of BALB/c NK cells, we have undertaken NK1.1 epitope mapping and genomic analysis of the BALB/c Nkrp1 region. Bacterial artificial chromosome library analysis reveals that, unlike...

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PMID: 16751398
DOI: 10.4049/jimmunol.176.12.7511

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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