Article
Diversity of human T cell receptor sequences of T cell clones with specificity for Bet v 1 peptide/MHC II complexes.
Advances in experimental medicine and biology - 1 Jan 1996
Breiteneder H, Hajek R, Hüttinger R, Ebner C, Schenk S, Kraft D, Scheiner O
Abstract excerpt
T cell clones (TCC) were raised from the peripheral blood of patients suffering from tree pollen allergy. All TCC were restricted by HLA-DR molecules. In order to investigate possible intervention targets in Type I allergic diseases, we have examined T cell receptor (TCR) alpha- and beta-chain nucleotide sequences of several allergen-reactive human CD4+ TCC specific for four frequently found epitopes of Bet v 1,...
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