Article
Diversity of human T cell receptor sequences of T cell clones with specificity for Bet v 1 peptide/MHC II complexes.
Advances in experimental medicine and biology - 1 Jan 1996
Breiteneder H, Hajek R, Hüttinger R, Ebner C, Schenk S, Kraft D, Scheiner O
Abstract excerpt
T cell clones (TCC) were raised from the peripheral blood of patients suffering from tree pollen allergy. All TCC were restricted by HLA-DR molecules. In order to investigate possible intervention targets in Type I allergic diseases, we have examined T cell receptor (TCR) alpha- and beta-chain nu...
Topics
- Allergens
- Amino Acid Sequence
- Antigens, Plant
- Base Sequence
- CD4-Positive T-Lymphocytes
- Clone Cells
- DNA
- Epitopes, T-Lymphocyte
- Genetic Variation
- HLA-DR Antigens
- Histocompatibility Testing
- Humans
- Molecular Sequence Data
- Peptides
- Plant Proteins
- Receptors, Antigen, T-Cell, alpha-beta
- Recombinant Proteins