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Article

Tracing antigen signatures in the human IgE repertoire.

Molecular immunology - 1 Aug 2010

Marth Katharina, Novatchkova Maria, Focke-Tejkl Margarete, Jenisch Stefan, Jäger Siegfried, Kabelitz Dieter, Valenta Rudolf

Abstract excerpt

Allergen recognition by IgE antibodies is a key event in allergic inflammation. In this study, the IgE IGHV repertoires of individuals with allergy to the major birch pollen allergen, Bet v 1, were analyzed over a four years period of allergen exposure by RT-PCR and sequencing of cDNA. Approximately half of the IgE transcripts represented non-redundant sequences, which belonged to seventeen different IGHV genes....

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Share to Antigens, Plant

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Genes, Immunoglobulin Heavy Chain

Share to Immunoglobulin E

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Share to Rhinitis, Allergic, Seasonal

Source

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Identifiers

PMID: 20573403
DOI: 10.1016/j.molimm.2010.05.285
PMCID: PMC2981859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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