Healthy human T-cell receptor beta-chain repertoire. Quantitative analysis and evidence for J beta-related effects on CDR3 structure and diversity.

doi:10.1016/0198-8859(95)00013-t

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Article

Healthy human T-cell receptor beta-chain repertoire. Quantitative analysis and evidence for J beta-related effects on CDR3 structure and diversity.

Human immunology - 1 Jul 1995

Hall M A, Lanchbury J S

Abstract excerpt

Analysis of TCR repertoire usage and clonality is of potential value in understanding the pathogenesis of a number of human immune-mediated diseases. In diseases that are likely to be dependent on antigen-driven T cells, it has been suggested that particular TCR junctional region or CDR3 sequence...

Topics

Adult
Amino Acid Sequence
Base Sequence
DNA
Female
Gene Expression
Genetic Variation
Humans
Immunoglobulin Joining Region
Immunoglobulin Variable Region
Male
Molecular Sequence Data
Polymerase Chain Reaction
Receptors, Antigen, T-Cell, alpha-beta

Source

Open in PubMed

Identifiers

PMID: 7558938
DOI: 10.1016/0198-8859(95)00013-t

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7558938-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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