Article
Healthy human T-cell receptor beta-chain repertoire. Quantitative analysis and evidence for J beta-related effects on CDR3 structure and diversity.
Human immunology - 1 Jul 1995
Hall M A, Lanchbury J S
Abstract excerpt
Analysis of TCR repertoire usage and clonality is of potential value in understanding the pathogenesis of a number of human immune-mediated diseases. In diseases that are likely to be dependent on antigen-driven T cells, it has been suggested that particular TCR junctional region or CDR3 sequences may be critical. Rigorous methods for TCR analysis which are both quantitative and qualitative are therefore...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
