Article
HLA-DR restricted peptide candidates for bee venom immunotherapy.
Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2000
Texier C, Pouvelle S, Busson M, Hervé M, Charron D, Ménez A, Maillère B
Abstract excerpt
T cell epitopes containing peptides have been recently proposed as an alternative to conventional immunotherapy of allergic diseases because they are expected to be better tolerated than allergen extracts. A principal limitation to their clinical use is that they present an important diversity, which primarily results from the polymorphism of HLA class II molecules. In Caucasian populations, however, seven...
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