Article
Interaction among human leucocyte antigen-peptide-T cell receptor complexes in cow's milk allergy: the significance of human leucocyte antigen and T cell receptor-complementarity determining region 3 loops.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 May 2002
Sakaguchi H, Inoue R, Kaneko H, Watanabe M, Suzuki K, Kato Z, Matsushita S, Kondo N
Abstract excerpt
BACKGROUND: Allergic individuals respond to only a few specific antigens, therefore allergic diseases are characterized by antigen specificity. Clarification of the mechanism of antigen specificity will lead to progress in the therapy of allergic diseases. OBJECTIVES: The purpose of this study is to determine the specific association among T cell epitopes, antigen-presenting molecules and T cell receptor (TCR),...
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