Article
Functional analysis of birch pollen allergen Bet v 1-specific regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 2007
Nagato Toshihiro, Kobayashi Hiroya, Yanai Mitsuru, Sato Keisuke, Aoki Naoko, Oikawa Kensuke, Kimura Shoji, Abe Yusuke, Celis Esteban, Harabuchi Yasuaki, Tateno Masatoshi
Abstract excerpt
Allergen-specific immunotherapy using peptides is an efficient treatment for allergic diseases. Recent studies suggest that the induction of CD4+ regulatory T (Treg) cells might be associated with the suppression of allergic responses in patients after allergen-specific immunotherapy. Our aim was to identify MHC class II promiscuous T cell epitopes for the birch pollen allergen Bet v 1 capable of stimulating Treg...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
