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Article

Paternal transmission of the mouse Thp mutation is lethal in some genetic backgrounds.

Developmental genetics - 1 Jan 1997

Rogers I, Okano K, Varmuza S

Abstract excerpt

Thp is a large deletion on chromosome 17 which includes the maternal lethal gene Tme. Documentation of inheritance patterns suggests that Tme is an imprinted gene which is required for viability; maternal deletion is lethal while paternal deletion is viable. However, paternal transmission of Thp is rarely the expected 50%. We show here that paternally inherited Thp is lethal in some strains, providing evidence of...

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Share to Abnormalities, Multiple
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9094208
DOI: 10.1002/(SICI)1520-6408(1997)20:1<23::AID-DVG3>3.0.CO;2-B

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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