Maternal Thp lethality in the mouse is a nuclear, not cytoplasmic, defect.

doi:10.1038/308550a0

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Article

Maternal Thp lethality in the mouse is a nuclear, not cytoplasmic, defect.

Nature - 1 Jan 2000

McGrath J, Solter D

Abstract excerpt

The Thp mutation, an allele of the mouse T/t complex, differs from other known mutations in that its effects are determined by the sex of the parent from which it is inherited; when inherited from the female parent, it is invariably lethal at the embryonic stage, but, most embryos which inherit t...

Topics

Alleles
Animals
Cell Nucleus
Embryo, Mammalian
Female
Fertilization in Vitro
Genes, Lethal
Male
Mice
Mice, Mutant Strains
Mutation
Nuclear Transfer Techniques
Phenotype

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