Article
The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus.
Nature - 3 Jan 1991
Barlow D P, Stöger R, Herrmann B G, Saito K, Schweifer N
Abstract excerpt
T-associated maternal effect (Tme) is the only known maternal-effect mutation in the mouse. The defect is nuclear-encoded and embryos that inherit a deletion of the Tme locus from their mother die at day 15 of gestation. There are many genomically imprinted regions known in the mouse genome but s...
Topics
- Animals
- Chromosome Deletion
- Chromosome Mapping
- Gene Expression Regulation
- Insulin-Like Growth Factor II
- Mice
- Mutation
- Receptors, Cell Surface
- Receptors, Somatomedin