Article
Gametic imprinting and the manifestation of the fused gene in the house mouse.
Developmental genetics - 1 Jan 1990
Ruvinsky A O, Agulnik A I
Abstract excerpt
The phenomenon of gametic imprinting in mammals has raised developmentally relevant questions concerning the manifestation and inheritance of genes with variable penetrance. The dominant fused (Fu) gene located on chromosome 17 is one of the few good cases demonstrating the phenomenon in mice. The Fu mutation has a maternal effect. We have previously shown that the t12 haplotype significantly lowers the...
Topics
- Animals
- Cloning, Molecular
- Embryonic and Fetal Development
- Female
- Gene Expression
- Genes, Dominant
- Genes, Suppressor
- Genetic Linkage
- Genotype
- Haplotypes
- Male
- Mice